Table 1 The drug susceptibility (IC50 value) of standard strains (K1 and 3D7) and field isolate PF91 after heat shock (HS) and non-heat shock (non-HS) condition.
From: The effect of mimicking febrile temperature and drug stress on malarial development
Parasite strain | Mean IC50 of drug susceptibility (nM) | |||
|---|---|---|---|---|
CQ | QN | MQ | ARS | |
K1 non-HS | 100.511 | 314.982 | 10.940 | 0.424 |
K1 HS | 104.468 | 300.071 | 11.259 | 0.862 |
3D7 non-HS | 11.332 | 47.117 | 18.208 | 0.434 |
3D7 HS | 4.722 | 43.936 | 15.470 | 0.660 |
PF91 non-HS | 63.585 | 37.886 | 8.124 | 1.254 |
PF91 HS | CC | CC | CC | CC |
K1 non-HS (NRF) | 100.511 | 314.982 | 10.940 | 0.425 |
K1 HS (NRF) | 104.468 | 300.072 | 11.260 | 0.862 |
3D7 non-HS (NRF) | 11.332 | 47.118 | 18.208 | 0.435 |
3D7 HS (NRF) | 4.722 | 43.937 | 15.470 | 0.661 |
PF91 non-HS (NRF) | 63.586 | 37.886 | 8.125 | 1.254 |
PF91 HS (NRF) | 63.586 | 37.886 | 8.125 | 0.954 |