Skip to main content

Advertisement

Table 1 The drug susceptibility (IC50 value) of standard strains (K1 and 3D7) and field isolate PF91 after heat shock (HS) and non-heat shock (non-HS) condition.

From: The effect of mimicking febrile temperature and drug stress on malarial development

Parasite strain Mean IC50 of drug susceptibility (nM)
  CQ QN MQ ARS
K1 non-HS 100.511 314.982 10.940 0.424
K1 HS 104.468 300.071 11.259 0.862
3D7 non-HS 11.332 47.117 18.208 0.434
3D7 HS 4.722 43.936 15.470 0.660
PF91 non-HS 63.585 37.886 8.124 1.254
PF91 HS CC CC CC CC
K1 non-HS (NRF) 100.511 314.982 10.940 0.425
K1 HS (NRF) 104.468 300.072 11.260 0.862
3D7 non-HS (NRF) 11.332 47.118 18.208 0.435
3D7 HS (NRF) 4.722 43.937 15.470 0.661
PF91 non-HS (NRF) 63.586 37.886 8.125 1.254
PF91 HS (NRF) 63.586 37.886 8.125 0.954
  1. NRF represents new ring infection when the parasite was cultured back to 37°C for one cycle.