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Table 3 MIC values for individual antibiotics alone (as determined by the broth microdilution method) and in effective synergistic combination with tigecycline (as determined by the chequerboard method) for seven A. baumannii isolates

From: In vitro activity of tigecycline in combination with various antimicrobials against multidrug resistant Acinetobacter baumannii

 

MIC (mg/L) a

Study code

TIG

LVX

AMK

IPM

CS

TIG/LVX

TIG/AMK

TIG/IPM

TIG/CS

5

4

16

64

16

0.25

0.25/4

NS

NS

NS

11

4

16

64

16

0.5

0.25/4

1/16

NS

NS

16

8

16

128

16

0.125

2/4

NS

NS

2/0.03

62

4

8

2

2

0.25

NS

NS

0.25/0.5

NS

71

4

8

256

16

0.5

NS

1/64

NS

NS

75

4

16

128

2

0.5

0.25/4

NS

NS

1/0.125

80

4

8

128

32

0.25

NS

NS

0.25/8

NS

  1. a Breakpoint criteria are provided in Additional file 1.
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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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