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Table 1 Patient demographics and culture source of Streptococcus pneumoniae isolates collected during the PROTEKT US study Years 1–4 (2000–2004)

From: Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1–4

  No. of isolates (%)
  Year 1 (n = 10,103) Year 2 (n = 10,012) Year 3 (n = 10,886) Year 4 (n = 8,494)
Age (years)     
   0–2 1,822 (18.0) 1,556 (15.5) 1,587 (14.6) 1,213 (14.3)
   3–14 1,105 (11.0) 1,125 (11.2) 1,324 (12.2) 973 (11.5)
   15–64 4,144 (41.0) 4,058 (40.5) 4,617 (42.4) 3,751 (44.2)
   > 64 2,761 (27.3) 3,067 (30.6) 3,091 (28.4) 2,378 (28.0)
   NR 271 (2.7) 206 (2.1) 267 (2.5) 179 (2.1)
Gender     
   Male 5,735 (56.8) 5,678 (56.7) 6,013 (55.2) 4,755 (56.0)
   Female 4,252 (42.1) 4,218 (42.1) 4,757 (43.7) 3,575 (42.1)
   NR 116 (1.1) 116 (1.2) 116 (1.1) 164 (1.9)
Source*     
   Blood 3,220 (31.9) 2,717 (27.1) 3,016 (27.7) 2,398 (28.2)
   BAL 968 (9.6) 1,019 (10.2) 1,197 (11.0) 993 (11.7)
   Sputum 3,736 (37.0) 4,115 (41.1) 4,595 (42.2) 3,428 (40.4)
   Sinus 388 (3.8) 390 (3.9) 506 (4.6) 446 (5.3)
   Ear 858 (8.5) 620 (6.2) 813 (7.5) 556 (6.5)
   MEF 68 (0.7) 69 (0.7) 91 (0.8) 88 (1.0)
   Nasopharyngeal 632 (6.3) 573 (5.7) 649 (6.0) 540 (6.4)
   Throat 48 (0.5) 28 (0.3) -- 6 (0.1)
Patient status     
   Inpatient 4,612 (45.6) 5,359 (53.5) 6,068 (55.7) 4,599 (54.1)
   Outpatient 5,287 (52.3) 4,349 (43.4) 4,818 (44.3) 3,776 (44.5)
   NR 204 (2.0) 304 (3.0) -- 119 (1.4)
  1. *Where isolate source was specified
  2. BAL, bronchoalveolar fluid; MEF, middle-ear fluid; NR, not recorded.