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Table 5 Activity of antibacterial agents against 468 isolates of Streptococcus pneumoniae collected from Japanese children (aged < 16 years) with community-acquired respiratory tract infections (combined data for all four 1-week study periods).

From: Mechanisms, molecular and sero-epidemiology of antimicrobial resistance in bacterial respiratory pathogens isolated from Japanese children

 

MIC (mg/L)

 

Antibacterial

Mode

MIC 50

MIC 90

Range

Susceptibility breakpoint

% susceptibility

Telithromycin

≤0.06

≤0.06

0.12

≤0.06–2

≤1

99.8

Erythromycin

>128

4

>128

≤0.06–>128

≤0.25

22.2

Azithromycin

>16

4

>16

≤0.06–>16

≤0.5

24.6

Cefdinir

4

1

8

≤0.06–32

≤2

58.8

Ampicillin

≤0.06

0.5

2

≤0.06–8

≤2

93.4

Amoxicillin-clavulanate

≤0.06

0.25

1

≤0.06–4

≤2

99.6