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Table 4 Genotyping analysis by erythromycin resistance phenotype of Streptococcus pneumoniae isolates (n = 468) collected from Japanese children (aged < 16 years) with community-acquired respiratory tract infections (combined data for all four 1-week study periods).

From: Mechanisms, molecular and sero-epidemiology of antimicrobial resistance in bacterial respiratory pathogens isolated from Japanese children

 

No. of isolates (%)

Genotype

ERY-S (n = 104)

ERY-I (n = 12)

ERY-R (n = 352)

erm(B)

5 (4.8)

3 (25.0)

207 (58.8)

erm(B) + mef(A)

1 (1.0)

0 (0.0)

8 (2.3)

mef(A)

1 (1.0)

7 (58.3)

131 (37.2)

erm(A) subclass erm(TR)

0 (0.0)

0 (0.0)

1 (0.3)

Negative for mechanisms tested

97 (93.3)

1 (8.3)

1 (0.3)

Not viable for testing

0 (0.0)

1 (8.3)

4 (1.1)

  1. ERY-I, erythromycin-intermediate (MIC 0.5 mg/L); ERY-R, erythromycin-resistant(MIC ≥ 1 mg/L); ERY-S, erythromycin-sensitive (MIC ≤ 0.25 mg/L).