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Table 2 Interaction of MUC7 12-mer in the combination with EDTA against C. albicans in the presence of Ca 2+

From: Factors affecting antimicrobial activity of MUC7 12-mer, a human salivary mucin-derived peptide

  

MIC (μM)

  

Ca 2+ (mM)

Pair

alone

combined

FIC

FICi

0

MUC7 12-mer

18.75

2.35

0.13

 
 

EDTA

75.00

6.25

0.09

0.22

0.01

MUC7 12-mer

25

6.25

0.25

 
 

EDTA

50

3.13

0.0626

0.3126

1

MUC7 12-mer

100

6.25

0.0625

 
 

EDTA

100

25

0.25

0.3125

2

MUC7 12-mer

200

6.25

0.03125

 
 

EDTA

200

50

0.25

0.28125

  1. All parameters (MIC, FIC, FICi) are defined in table 1 footnote.