Table 1 The use of Adefovir for the treatment of HBV graft infection
Author (Reference) | No of Patients | No patients DNA Pos | No patients HBeAg Pos | Treatment duration | DNA Negative following Treatment | HBeAG Seroconversion | DNA Change Median | Development of Adefovir Resistant Mutants |
|---|---|---|---|---|---|---|---|---|
Echanojauregui [82] | 7†| 7 | 5 | 48 weeks | 3 | 1 | -3.19 | None reported |
Schiff [71] | 196* | 172 | Not reported | 56.1 | 34 | Not reported | -4.3 | None reported |
Wai [16] | 4* | 4 | Not reported | 24 months (one only received 9 months of therapy) | 0 | Not reported | -2.0 | None reported |
Neff [19] | 9* | 9 | 7 | 6– 48 months Median 30 months | 0* | 4 | Not reported* | None reported |
Toniutto [22] | 1†| 1 | 0 | 2 months | 1 | N/A | Initial load not reported but became undetectable | No |
Beckebaum [83] | 1* | 1 | 1 | 15 months | 0 | 0 | 2.45 billion to 32, 100 | No |
Akay [17] | 2* | 2 | Not reported | 4 months | 2 | Not reported | 2000 and 17 pg/mL respectively to undetectable | No |