Skip to main content

Table 3 Concentrations of the naphthoquinones used in dermal irritability test

From: Tabebuia avellanedae naphthoquinones: activity against methicillin-resistant staphylococcal strains, cytotoxic activity and in vivo dermal irritability analysis

Compound MIC 100× MIC
I 0.03 % (256 μg/mL) ND
II 0.01 % (64 μg/mL) ND
III 0.001% (8 μg/mL) ND
IV 0.001% (8 μg/mL) 0.1 % (800 μg/mL)
  1. N.D. → not determined. MIC = Minimal Inhibitory Concentration. Compounds: I) Lapachol; II) α-lapachone; III) β-lapachone; IV) (±) 3-hydroxy-β-N-lapachone.