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Table 3 Concentrations of the naphthoquinones used in dermal irritability test

From: Tabebuia avellanedae naphthoquinones: activity against methicillin-resistant staphylococcal strains, cytotoxic activity and in vivo dermal irritability analysis

Compound

MIC

100× MIC

I

0.03 % (256 μg/mL)

ND

II

0.01 % (64 μg/mL)

ND

III

0.001% (8 μg/mL)

ND

IV

0.001% (8 μg/mL)

0.1 % (800 μg/mL)

  1. N.D. → not determined. MIC = Minimal Inhibitory Concentration. Compounds: I) Lapachol; II) α-lapachone; III) β-lapachone; IV) (±) 3-hydroxy-β-N-lapachone.
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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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