week 4 | week 12 | week 24 | week 48 | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDR1 | n = | median [cells/μl] | mean [cells/μl] | SA | p = | n = | median [cells/μl] | mean [cells/μl] | SA | p = | n = | median [cells/μl] | mean [cells/μl] | SA | p = | n = | median [cells/μl] | mean [cells/μl] | SA | p = | |
2677 | GG | 24 | 56,5 | 69,8 | 81,5 | >0.3 | 22 | 97,0 | 130,6 | 132,4 | >0.5 | 21 | 107,0 | 136,1 | 120,5 | >0.8 | 15 | 244,0 | 235,7 | 132,1 | >0.1 |
GT | 23 | 24,0 | 37,8 | 82,5 | 20 | 84,5 | 144,3 | 157,2 | 17 | 132,0 | 180,8 | 178,0 | 16 | 161,5 | 238,3 | 218,6 | |||||
TT | 18 | 9,5 | 67,4 | 117,7 | 16 | 70,0 | 143,9 | 222,3 | 16 | 95,0 | 154,5 | 162,0 | 14 | 107,5 | 143,9 | 159,1 | |||||
AG | 4 | 70,5 | 85,8 | 68,5 | § | 4 | 82,5 | 74,8 | 34,4 | § | 4 | 54,5 | 80,3 | 81,3 | § | 4 | 131,5 | 126,5 | 71,0 | § | |
AT | 3 | 112,0 | 105,7 | 13,4 | § | 3 | 176,0 | 180,7 | 63,8 | § | 2 | 154,5 | 154,5 | 54,5 | § | 3 | 172,0 | 248,0 | 118,2 | § | |
3435 | CC | 20 | 76,0 | 84,8 | 78,6 | >0.1 | 19 | 91,0 | 123,0 | 113,0 | >0.9 | 18 | 106,5 | 132,4 | 112,4 | >0.5 | 13 | 191,0 | 220,1 | 121,5 | >0.6 |
CT | 34 | 25,5 | 47,2 | 76,1 | 30 | 85,0 | 123,7 | 135,3 | 28 | 131,0 | 134,2 | 106,8 | 25 | 159,0 | 187,7 | 118,4 | |||||
TT | 18 | 12,0 | 61,6 | 119,1 | 17 | 74,0 | 175,9 | 228,1 | 16 | 134,0 | 212,2 | 214,7 | 15 | 122,0 | 223,9 | 259,3 | |||||
2677/3435† | H1 | 17 | 72,0 | 83,1 | 78,7 | >0.1 | 16 | 115,0 | 132,1 | 119,8 | >0.8 | 15 | 107,0 | 142,2 | 113,3 | >0.9 | 10 | 194,0 | 239,6 | 128,4 | >0.5 |
H2 | 41 | 20,0 | 50,8 | 100,6 | 36 | 74,5 | 144,1 | 188,9 | 33 | 130,0 | 168,1 | 170,9 | 30 | 134,5 | 194,2 | 198,8 | |||||
H3 | 7 | 19,0 | 37,3 | 79,1 | § | 6 | 92,0 | 126,7 | 161,2 | § | 6 | 122,0 | 120,8 | 135,7 | § | 5 | 302,0 | 227,8 | 138,9 | § | |
H5 | 7 | 87,0 | 94,3 | 53,5 | § | 7 | 105,0 | 120,1 | 71,9 | § | 7 | 100,0 | 131,0 | 98,7 | § | 7 | 172,0 | 178,6 | 111,7 | § | |
total | 72 | 65 | 61 | 52 |