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Table 3 Immune Profiles of Patients with Chronic Hepatitis due to Coinfection, and Suggested Treatments Based on Published Trials

From: Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection

Immune profile HBV DNA HBsAg HBeAg HCV RNA Anti-HCV Possible treatments [ref]
Dually active + +/- +/- + + IFN alone [54] IFN + ribavirin [57-59] IFN + lamivudine [61]
Active HCV in HBV carrier - + - + + IFN alone [23, 53, 55] IFN + ribavirin [57-59]
Active HBV in chronic HCV + - - + + IFN alone [10] IFN + lamivudine [61]
Silent HBV + - - +/- + IFN alone [10] IFN + lamivudine [61]
  1. Abbreviations: HCV = hepatitis C virus; HBV = hepatitis B virus; DNA = deoxyribonucleic acid; RNA = ribonucleic acid; HBsAg = Hepatitis B surface antigen; HBeAg = Hepatitis B e antigen; Anti-HCV = antibody to hepatitis C virus; IFN = interferon