Prior antimicrobial therapy in the hospital and other predisposing factors influencing the usage of antibiotics in a pediatric critical care unit

Table 3 Multiple regression analyses of the range of antibiotic coverage related to various independent clinical determinants

Dependent variable	Independent determinant	p value
Cumulative number of antibiotics	Prior administration of antibiotics	.0001
	Presence of a bloodstream infection	.0001
	Positive bronchial cultures	.0001
	Negative outcome	.0001
	Severity of illness (PRISM)	.03
	Development of MOSF	.002
	Immunodeficiency	.001
	Number of central catheters	.03
Maximum daily number of antibiotics	Interventional TISS	.007
Duration of antibiotic coverage	Length of stay	.0001

ISSN: 1476-0711