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Table 2 Susceptibility of nonmeningeal isolates of S. pneumoniae recovered from January 2002 to June 2003 to expanded-spectrum cephalosporins using both M100-S11 and M100-S12 NCCLS standards

From: Tracking the implementation of NCCLS M100-S12 expanded-spectrum cephalosporin MIC breakpoints for nonmeningeal isolates of Streptococcus pneumoniae by clinical laboratories in the United States during 2002 and 2003

Antimicrobial agent

Total no. of isolates

NCCLS standard

% Susceptible

% Intermediate

% Resistant

Ceftriaxone

7,940

M100-S11

86.9

9.9

3.2

  

M100-S12

96.8

2.3

1.0

Cefotaxime

4,887

M100-S11

82.4

13.5

4.1

  

M100-S12

95.9

2.6

1.5