From: Tracking the implementation of NCCLS M100-S12 expanded-spectrum cephalosporin MIC breakpoints for nonmeningeal isolates of Streptococcus pneumoniae by clinical laboratories in the United States during 2002 and 2003
Antimicrobial agent
Total no. of isolates
NCCLS standard
% Susceptible
% Intermediate
% Resistant
Ceftriaxone
7,940
M100-S11
86.9
9.9
3.2
M100-S12
96.8
2.3
1.0
Cefotaxime
4,887
82.4
13.5
4.1
95.9
2.6
1.5