Skip to main content

Table 1 Results of the first phase of the animal study

From: The effect of indomethacin, myeloperoxidase, and certain steroid hormones on bactericidal activity: an ex vivo and in vivo experimental study

  1. M0 2. I0 3. Mi 4. Ii p < 0.05
Treatment None (methylcellulose) Indomethacin None (methylcellulose) Indomethacin  
Infection No No Yes Yes  
Colony patterns:    Heart blood Liver Heart blood Liver  
None    2 1 0 0  
1-10 colonies    3 2 2 1  
Dense, but separate    1 4 1 1  
Confluent    2 1 5 6  
Sample number for lab tests 6 5 6 7  
WBC (×109/l) 7.72 ± 2.06 5.09 ± 3.53 5.95 ± 2.61 9.28 ± 1.87 4 vs 2,3
Neutrophil (%) 18.00 ± 4.53 47.40 ± 26.10 22.83 ± 5.64 30.83 ± 9.30 ns
Lymphocyte (%) 80.00 ± 4.36 49.00 ± 28.10 73.67 ± 6.47 64.50 ± 9.22 ns
RBC (×1012/l) 5.94 ± 0.68 3.86 ± 1.52 5.66 ± 0.39 3.66 ± 1.09 4 vs 1
HGB (g/dl) 110.00 ± 9.00 73.40 ± 29.20 105.67 ± 6.83 68.50 ± 18.22 4 vs 1
HCT (l/l) 0.39 ± 0.03 0.26 ± 0.11 0.38 ± 0.03 0.25 ± 0.07 4 vs 1
Total protein (g/l) 55.65 ± 2.49 52.20 ± 4.65 59.22 ± 3.00 42.00 ± 7.86 4 vs 3
Albumin (g/l) 27.92 ± 0.98 22.88 ± 3.13 26.07 ± 0.65 19.80 ± 3.65 4 vs 1
Globulin (g/l) 27.73 ± 1.63 29.32 ± 2.79 33.15 ± 2.63 22.20 ± 4.30 3 vs 1,2,4; 4 vs 1,2
CRP (mg/dl) 300.00 ± 25.20 306.60 ± 32.90 411.67 ± 55.98 261.71 ± 72.99 3 vs 1,2,4
  1. The number of different P. multocida colony shapes and laboratory results (means ± SD). The last column shows the groups where significant differences were found. ns: not significant.