From: Factors predicting prolonged empirical antifungal treatment in critically ill patients
Patient characteristics | Prolonged empirical antifungal treatment | p value | |
---|---|---|---|
Yes n = 77 | No n = 76 | ||
Multifocal fungal colonization | 24 (31) | 35 (46) | 0.076 |
Antimicrobial treatment | 73 (94) | 70 (93) | 0.744 |
Mechanical ventilation | 59 (76) | 67 (88) | 0.059 |
Duration of mechanical ventilation, d | 12.5 (4, 25) | 20 (0, 36) | 0.007 |
Central venous catheter | 69 (89) | 71 (93) | 0.396 |
Duration of central venous catheter use, d | 13 (4, 20) | 18 (10, 25) | 0.015 |
Arterial catheter | 62 (81) | 71 (93) | 0.025* |
Duration of arterial catheter use, d | 8 (3, 15) | 13 (10, 20) | 0.002 |
Dialysis | 30 (39) | 28 (37) | 0.97 |
Parenteral nutrition | 26 (33) | 29 (38) | 0.571 |
Duration of antifungal treatment, d | 9 (4, 19) | 6 (2, 11) | 0.003 |
Percentage of days in the ICU with antifungals | 80 (65, 100) | 25 (13, 35) | <0.001 |
Length of ICU stay, d | 14 (5, 27) | 22 (14, 39) | 0.001 |
ICU mortality | 36 (46) | 39 (52) | 0.518 |