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Table 4 In vitro susceptibility of the clinical isolates to 6 antimicrobials

From: A multicentre clinical study on the injection of ceftriaxone/sulbactam compared with cefoperazone/sulbactam in the treatment of respiratory and urinary tract infections

Isolates

 

Cefoperazone-sulbactam

Cefoperazone

Ceftriaxone-sulbactam

Ceftriaxone

Imipenem

Cefepime

 

MICr

32–4

128–64

32–81

28–64

8–1

16–2

E. coli(153)

MIC50

16

64

8

64

1

4

 

MIC90

32

128

32

128

4

16

 

MICr

32–2

128–32

16–2

128–32

4–1

16–2

K. pneumoniae(22)

MIC50

8

64

4

64

1

4

 

MIC90

32

128

16

128

2

8

 

MICr

32–4

128–32

32–8

128–64

8–2

16–2

E cloacae(18)

MIC50

16

32

8

64

2

4

 

MIC90

32

128

32

128

4

16

 

MICr

32–8

128–64

16–4

128–64

4–1

8–1

E. aerogenes(13)

MIC50

8

64

16

64

1

2

 

MIC90

32

128

32

128

2

8

Proteus spp(6)

MICr

8–4

64–32

4–2

32–16

2–1

8–1

 

MICr

32–4

128–32

32–8

128–32

64–4

64–8

A. baumannii(12)

MIC50

8

32

8

32

8

16

 

MIC90

16

128

32

128

64

64

 

MICr

32–2

128–4

32–4

128–8

64–4

32–4

P. aeruginosa(10)

MIC50

8

32

16

64

4

8

 

MIC90

32

128

32

128

32

32

S. aureus(5)

MICr

32–16

64–32

32–16

64–32

16–2

8–4

S. haemolyticus(9)

MICr

32–16

64–32

32–8

64

16–2

8–4

  1. MIC: minimum inhibitory concentration; MIC50: Minimum Inhibitory Concentration required to inhibit the growth of 50% of organisms; MIC90: Minimum Inhibitory Concentration required to inhibit the growth of 90% of organisms; MICr: Range of MIC.