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Table 4 General characteristics of the patients with renal insufficiency at the beginning and in the course of treatment

From: Colistin use in pediatric intensive care unit for severe nosocomial infections: experience of an university hospital

Patient number

Age & gender

Time of RI

Type of RI

BUN, creatinine at the beginning of treatment

BUN, creatinine at the end of treatment

Concomitants nephrotoxic agent use

Type and duration of RRT

Duration of treatment

Outcome

P4

11/M

Before treatment

Oliguric ARF

36/1.3

23/1.6

Amphotericin B

One day of hemodialysis

19

Survey

P8

7/M

During the treatment

Oliguric ARF

8/0.2

53/5.6

Aminoglycoside, glycopeptides

14 days of peritoneal dialysis

22

Survey

P12

2.5/F

During the treatment

Non-oliguric ARF

7/0.2

20/1.6

Aminoglycoside

Colistin treatment was halted

8

Survey

RRT was not performed

P15

12/F

During the treatment

Non-oliguric ARF

7/0.2

89/3.2

Glycopeptides, amphotericin B

RRT was not performed

8

Death*

P26

17/M

Before treatment

CRF

66/2.5

111/2.5

Non

8 days of hemodialysis

10

Death*

P38

7/M

Before treatment

ARF

76/2.3

38/1.2

Glycopeptides

4 days of peritoneal dialysis

4

Death**

  1. * Infection-related death, ** Infection-unrelated death, BUN: Blood urea nitrogen, RI: Renal impairment, RRT: Renal replacement therapy, ARF: Acute renal failure, CRF: Chronic renal failure.