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Table 3 Acute oral toxicity of the extract of A. crassna leaves in mice

From: Antibacterial activity of Aquilaria crassna leaf extract against Staphylococcus epidermidis by disruption of cell wall

Treatment (mg/kg)

sex

Body weight (g)

Mortality

Symtoms of toxicity

Gross pathology

  

Day 1

Day 8

Day 15

   

0

 

33.20 ± 1.52

37.06 ± 1.52

41.00 ± 1.73

0

None

Normal

2000

Male

32.80 ± 1.30

37.20 ± 0.84

41.00 ± 1.00

0

None

Normal

15000

 

34.40 ± 1.14

39.80 ± 0.84

43.20 ± 0.84

0

None

Normal

0

 

28.40 ± 1.67

30.80 ± 2.17

34.00 ± 1.58

0

None

Normal

2000

Female

28.00 ± 1.22

30.00 ± 1.22

33.2 ± 1.64

0

None

Normal

15000

 

28.80 ± 1.30

31.80 ± 1.30

34.00 ± 1.00

0

None

Normal

  1. Value are expressed as means ± standard deviation (n = 5); p> 0.05 compared to control.