Table 2 Results of adaptive resistant experiments of selected carbapenem-resistant Acinetobacter baumannii isolates
Strain | PFGE group | MIC (mg/L) | Polymyxin B MIC of subpopulations selected in PAP | Highest concentration of polymyxin B where growth was observed (mg/L) | MIC after 3 days daily passages in drug-free medium (mg/L) | MIC after 60 days storage (mg/L) |
|---|---|---|---|---|---|---|
2 | A | ≤ 0.125 | 2 | 64 | 32 | NP |
3 | A | 0.25 | NA | 64 | 16 | NP |
5 | A | 0.25 | 1 | NG | NA | NA |
6 | A | 1 | 1 | 64 | 16 | NP |
7 | B | ≤ 0.125 | 0.5 | 64 | 16 | NP |
8 | B | 0.25 | 1 | 64 | 16 | NP |
9 | B | ≤ 0.125 | 0.5 | 64 | 16 | NP |
10 | C | ≤ 0.125 | 1 | 64 | 32 | ≤ 0.125 |
12 | C | ≤ 0.125 | 1 | 64 | 16 | NP |
14 | D | ≤ 0.125 | 1 | NG | NA | NA |
15 | E | 0.25 | 1 | NG | NA | NA |
16 | F | 0.5 | 2 | NG | NA | NA |
17 | F | ≤ 0.125 | 1 | NG | NA | NA |
18 | G | 0.25 | 1 | 64 | ≥ 64 | NP |
19 | H | 0.25 | 1 | NG | NA | NA |
20 | I | 0.25 | 2 | NG | NA | NA |
22 | J | 0.25 | 1 | 64 | 16 | 0.25 |
23 | K | 0.25 | NA | NG | NA | NA |
24 | L | ≤ 0.125 | 0.5 | 64 | 16 | ≤ 0.125 |
26 | M | ≤ 0.125 | 1 | 64 | ≥ 64 | ≤ 0.125 |
27 | N | 0.5 | 2 | NG | NA | NA |
29 | O | ≤ 0.125 | 1 | NG | NA | NA |