Impact of a multidimensional infection control approach on central line-associated bloodstream infections rates in adult intensive care units of 8 cities of Turkey: findings of the International Nosocomial Infection Control Consortium (INICC)

Table 3 Characteristics of patients, hand hygiene compliance, central line care compliance, central line usage, central line-associated blood stream infection rates, in the baseline period and intervention period

Patients’ characteristics	Baseline	Intervention	RR*	95% CI	P- Value
Study period by hospital in months, mean ± SD (range)	3	15.6 ± 9.2 (4 – 36)
Number of Patients	560	3457
*Bed days, n	5517	37232
**No. of CL days, n	3129	23463
***CL use, mean	0.57	0.63	1.1	1.07 – 1.15	0.0001
CL duration, mean ± SD	5.6 ± 9.0	6.8 ± 11.0	-	-	0.014
Age, mean ± SD	54.1 ± 22.0	52.3 ± 21.4	-	-	0.08
ASIS score, mean ± SD	3.2 ± 1.1	3.6 ± 1.14	-	-	0.0001
Male	305 (57%)	2,048 (60%)	1.05	0.91 – 1.21	0.5
Female	230 (43%)	1379 (40%)	-	-	-
Abdominal Surgery, n (%)	58 (10%)	349 (10%)	0.97	0.74 – 1.3	0.84
Cardiac Surgery, n (%)	11 (2%)	72 (2%)	1.1	0.56 – 2.22	0.9
Trauma, n (%)	58 (10%)	357 (10%)	0.99	0.75 – 1.34	0.97
Previous Infections, n (%)	81 (14%)	415 (12%)	0.83	0.653 – 1.1	0.13
Endocrine diseases, n (%)	43 (8%)	250 (7%)	0.94	0.68 – 1.33	0.7
Chronic Obstructive, n (%)	150 (27%)	904 (26%)	0.98	0.82 – 1.17	0.8
Renal Impairment, n (%)	33 (6%)	180 (5%)	0.9	0.61 – 1.3	0.5
Hepatic Failure, n (%)	13 (2%)	50 (1%)	0.62	0.33 – 1.25	0.14
Thoracic Surgery, n (%)	27 (5%)	151 (4%)	0.91	0.6 – 1.42	0.62
Stroke, n (%)	14 (3%)	64 (2%)	0.74	0.4 – 1.43	0.3
Hand Hygiene compliance % (n/n)	32% (427/1328)	49% (5260/10786)	1.52	1.4 – 1.7	0.0001
Date on administration set % (n/n)	33% (1544/4656)	39% (14159/36472)	1.17	1.11 – 1.2	0.0001
Placed sterile dressing % (n/n)	78% (3617/4656)	90% (32895/36472)	1.2	1.12 – 1.2	0.0001
Correct condition of dressing % (n/n)	76% (3537/4656)	73% (26699/36472)	0.96	0.93 – 0.99	0.04
No. of CLAB, n	71	372
CLAB Rate per 1000 CL days	22.7	15.85	0.7	0.54 – 0.91	0.008

SD, standard deviation; CL, central line; CLAB, Central line associated bloodstream infection; RR, relative risk; CI, confidence interval; ASIS, average severity of illness score.
*Bed-days are the total number of days that patients are in the ICU during the selected time period.
**CL-days: the total number of days of exposure to central line by all of the patients in the selected population during the selected time period.
***CL use ratios were calculated by dividing the total number of CL-days by the total number of bed-days.

ISSN: 1476-0711