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Table 1 MICs of antifungals alone and in combination with CSA against C. albicans

From: Sensitization of Candida albicans biofilms to various antifungal drugs by cyclosporine A

Name of Drug

Minimum Inhibitory Concentration (μg/ml)

 

Planktonic cellsa

Biofilm developmentb

Mature biofilmsb

 

Drug alone

Drug + 62.5 μg/ml CSA

Drug alone

Drug + 62.5 μg/ml CSA

Drug alone

Drug + 62.5 μg/ml CSA

FLC

0.5

0.031

512

1

1024

2

VOR

0.125

0.031

2

0.063

4

0.061

CSP

0.25

0.063

0.5

0.063

1

0.125

AmB

0.5

0.5

0.5

0.031

0.5

0.5

NYT

1

0.25

3

3

3

3

  1. a Measured in terms of absorbance of cell density b Measured in terms of percentage RMA obtained in XTT assay.