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Table 1 Bacteriostatic (−) and Bactericidal (+) effects of Alkaloid compounds from Cienfuegosia digitata Cav. and their combination with Methicillin and with Ampicillin

From: Antibacterial activity against β- lactamase producing Methicillin and Ampicillin-resistants Staphylococcus aureus: fractional Inhibitory Concentration Index (FICI) determination

Microorganisms

Meth + Alkaloids

Amp + Alkaloids

Alkaloid Fractions

MRSA/ARSA-01

+

+

+

MRSA/ARSA-02

-

-

-

MRSA/ARSA-03

-

-

-

MRSA/ARSA-04

+

-

-

MRSA/ARSA-05

-

+

-

MRSA/ARSA-06

+

-

-

MRSA/ARSA-07

-

-

-

MRSA/ARSA-08

-

-

-

MRSA/ARSA-09

+

-

-

MRSA/ARSA-10

-

+

-

MRSA/ARSA-11

-

-

-

MRSA/ARSA-12

+

+

+

MRSA/ARSA-13

-

-

-

MRSA/ARSA-14

+

+

+

MRSA/ARSA-15

-

-

-

  1. The results are the means of number of the colonies ± standard deviations.
  2. +: bactericidal effect (MBC/MIC = 1 or 2) –: bacteriostatic effect (MBC/MIC = 4 or 16).