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Table 1 Mouse treatment regimen

From: Decrease in Shiga toxin expression using a minimal inhibitory concentration of rifampicin followed by bactericidal gentamicin treatment enhances survival of Escherichia coli O157:H7-infected BALB/c mice

Group

First Injection

(Hour 0)

Second Injection

(Hour 1)

Third Injection

(Hour 17)

1

E. coli O157:H7 (3 × LD50)

Rifampicin (MIC)

-

2

E. coli O157:H7 (3 × LD50)

Gentamicin (MBC)

-

3

E. coli O157:H7 (3 × LD50)

Rifampicin (MIC)

Gentamicin (MBC)

4

E. coli O157:H7 (3 × LD50)

Rifampicin (MIC)

Rifampicin (MBC)

5

Trypticase soy broth

Trypticase soy broth

Trypticase soy broth

6

Trypticase soy broth

Rifampicin (MIC)

Gentamicin (MBC)

7

E. coli O157:H7 (3 × LD50)

-

-