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Table 2 Minimum inhibitory and minimum bactericidal concentrations in μg/ml of benzalkonium with and without thymoquinone supplementation.

From: Antibacterial and resistance-modifying activities of thymoquinone against oral pathogens

Strains

MIC

BC

MBC BC

aMIC BC +

1/2MIC TQ

aMBC BC +1/2 MIC TQ

References strains

    

B. cereus ATCC 14579

16

32

4 (4)

8 (4)

E. coli ATCC 35218

16

32

16 (NC)

16 (2)

E. faecalis ATCC 29212

8

16

4 (2)

4 (4)

L. monocytogenes ATCC 19115

1

4

1 (NC)

2 (2)

M. luteus NCIMB 8166

16

16

2 (8)

4 (4)

S. enterica serovar Typhimurium ATCC 1408

32

64

32 (NC)

64 (NC)

S. aureus ATCC 25923

16

32

2 (8)

4 (8)

S. epidermidis CIP 106510

4

8

2 (2)

4 (2)

P. aeruginosa ATCC 27853

128

256

128 (NC)

256 (NC)

V. alginolyticus ATCC 33787

32

64

16 (2)

32 (2)

V. paraheamolyticus ATCC 17802

32

128

4 (8)

16 (8)

Oral strains

    

E. faecalis B281

256

>256

256 (NC)

>256 (NC)

Gemella haemolysans B234

8

32

4 (2)

8 (4)

S. aureus B73

16

32

2 (8)

8 (4)

S. aureus B285

8

16

2 (4)

4 (4)

S. aureus B291

16

16

2 (2)

4 (4)

S. aureus B289

8

16

<1 (>8)

2 (8)

S. aureus B456

4

8

<1 (>8)

2 (4)

S. aureus B244

2

8

<1 (>8)

2 (4)

S. aureus B364

64

128

8 (>8)

32 (4)

S. aureus B398

4

8

<1 (>8)

2 (4)

S. anginosus B486

8

16

4 (2)

8 (2)

S. constellatus B629

4

16

2 (2)

4 (4)

S. mitis B627

4

8

4 (NC)

16 (2)

S. mutans B509

4

8

2 (2)

4 (2)

S. oralis B634

>256

>256

>256 (NC)

>256 (NC)

S. salivarius B468

8

16

4 (2)

8 (2)

  1. aFold reductions are given in parentheses; NC, no change; TQ, Thymoquinone; BC, benzalkonium chloride