Table 1 Minimum inhibitory and minimum bactericidal concentrations in μg/ml of thymoquinone and tetracycline and their combination
From: Antibacterial and resistance-modifying activities of thymoquinone against oral pathogens
MIC TQ | MBC TQ | MIC TET | MBC TET | aMIC TET + 1/2MIC TQ | MBC TET + 1/2MIC TQ | |
|---|---|---|---|---|---|---|
References strains | ||||||
Bacillus cereus ATCC 14579 | 8 | 8 | 2 | 8 | 0.5 (4) | 4 (2) |
Escherichia coli ATCC 35218 | 512 | 512 | 4 | 16 | 2 (2) | 64 (4) |
Enterococcus faecalis ATCC 29212 | 32 | 128 | 256 | 512 | 128 (2) | 64 (8) |
Salmonella enterica serovar Typhimurium ATCC 1408 | 256 | 512 | 128 | 256 | 32 (4) | 128 (2) |
Staphylococcus aureus ATCC 25923 | 8 | 16 | 4 | 8 | 0.5 (8) | 4 (2) |
Staphylococcus epidermidis CIP 106510 | 8 | 8 | 8 | 16 | 4 (2) | 64 (4) |
Listeria monocytogenes ATCC 19115 | 32 | 128 | 1 | 4 | 1 (NC) | 4 (NC) |
Micrococcus luteus NCIMB 8166 | 8 | 64 | 32 | 64 | 8 (4) | 16 (4) |
Pseudomonas aeruginosa ATCC 27853 | >512 | >512 | 64 | 128 | 32 (2) | 256 (2) |
Vibrio alginolyticus ATCC 33787 | 512 | 512 | 256 | 512 | 128 (2) | 256 (2) |
Vibrio paraheamolyticus ATCC 17802 | 32 | 64 | 4 | 32 | 0.5 (8) | 8 (4) |
Oral strains | ||||||
E. faecalis B281 | 256 | 256 | 64 | 256 | 64 (NC) | 128 (2) |
Gemella haemolysans B234 | 128 | 128 | 512 | 256 | 256 (2) | 256 (NC) |
Staphylococcus aureus B73 | 256 | 256 | 64 | 128 | 16 (4) | 16 (8) |
Staphylococcus aureus B285 | 8 | 32 | 4 | 4 | 4 (NC) | 8 (2) |
Staphylococcus aureus B291 | 256 | 256 | 128 | 128 | 32 (4) | 64 (2) |
Staphylococcus aureus B289 | 16 | 16 | 4 | 4 | <0.5 (>8) | 2 (2) |
Staphylococcus aureus B456 | 16 | 32 | 32 | 128 | 4 (8) | 16 (8) |
Staphylococcus aureus B244 | 16 | 32 | 32 | 32 | 4 (8) | 8 (4) |
Staphylococcus aureus B364 | 256 | 256 | 4 | 8 | 8 (2) | 8 (NC) |
Staphylococcus aureus B398 | 8 | 16 | 16 | 16 | 4 (4) | 4 (4) |
Streptococcus anginosus B486 | 64 | 64 | 128 | 256 | 64 (2) | 128 (2) |
Streptococcus constellatus B629 | 32 | 64 | <0,5 | 4 | <0.5 (NC) | 4 (NC) |
Streptococcus mitis B627 | 128 | 256 | 128 | 256 | 32 (4) | 128 (2) |
Streptococcus mutans B509 | 16 | 16 | <0,5 | 8 | <0.5 (NC) | 4 (2) |
Streptococcus oralis B634 | 32 | 64 | 128 | 128 | 32 (4) | 64 (2) |
Streptococcus salivarius B468 | 16 | 32 | 4 | 16 | 2 (2) | 8 (2) |