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Table 2 Antifungal activities (MIC mM) of benzaldehyde derivatives tested on agar against filamentous fungi.

From: Antifungal activity of redox-active benzaldehydes that target cellular antioxidation

Compound A. fumigatus
AF293
A. terreus
UAB673
A. terreus
UAB680
A. terreus
UAB698
A. flavus
NRRL3357
P. expansum
NRRL974
Mean
MIC
Cinnamaldehyde 1.0 0.5 0.5 0.5 0.5 0.5 0.58 ± 0.201
2-Hydroxy-5-methoxy-
benzaldehyde
0.5 0.5 0.5 0.5 0.5 1.0 0.58 ± 0.201
2-Hydroxy-3-methoxy-
benzaldehyde (o-Vanillin)
0.5 0.5 0.5 0.5 1.0 1.0 0.67 ± 0.261
3,5-Dimethoxybenzaldehyde 1.0 1.0 1.0 1.0 1.5 1.5 1.17 ± 0.261
2,5-Dimethoxybenzaldehyde 1.5 1.5 1.5 1.0 1.5 2.0 1.50 ± 0.321
2-Methoxybenzaldehyde
(o-Anisaldehyde)
2.0 2.5 2.5 2.5 2.5 2.5 2.42 ± 0.201
2,3-Dimethoxybenzaldehyde 2.5 2.5 2.0 2.0 3.0 3.0 2.50 ± 0.451
Benzaldehyde
(Basal structure)
> 35.0 > 35.0 > 35.0 > 35.0 > 35.0 > 35.0 > 35.0
  1. 1 P < 0.0005 (Student's t test for paired data, i.e., vs. mean MIC of benzaldehyde).