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Table 2 Hemolytic activity of NP1P-NP3P and their parent peptides.

From: Generation of novel cationic antimicrobial peptides from natural non-antimicrobial sequences by acid-amide substitution

Agent

Concentration (μg/mL)

Hemolytic activity (%)

NP1P (P1P)

300

1.32 ± 0.02 (0.00 ± 0.00)

NP2P (P2P)

300

3.48 ± 0.01 (0.00 ± 0.01)

NP3P (P3P)

300

2.61 ± 0.02 (1.69 ± 0.05)

amphotericin B

30

82.5 ± 7.2