Table 2 The performance of mNGS in the prediction of carbapenems, penicillins and cephalosporins resistance
From: Antimicrobial resistance prediction by clinical metagenomics in pediatric severe pneumonia patients
Antibiotic type | TN | TP | FN | FP | Sensitivity (CI) | Specificity | PPV | NPV | Accuracy |
|---|---|---|---|---|---|---|---|---|---|
Carbapenems | 18 | 21 | 10 | 3 | 67.74% (48.54-82.68%) | 85.71% (62.64-96.24%) | 87.50% (66.54-96.71%) | 64.29% (44.11-80.69%) | 75.00% (60.77-85.52%) |
Penicillins | 9 | 2 | 5 | 3 | 28.57% (5.11-69.74%) | 75.00% (42.84-93.31%) | 40.00% (7.26-82.96%) | 64.29% (35.63-86.02%) | 57.89% (33.97-78.88%) |
Cephalosporins | 18 | 18 | 21 | 6 | 46.15% (30.43-62.62%) | 75.00% (52.95-89.40%) | 75.00% (52.95-89.40%) | 46.15% (30.43-62.62%) | 57.14% (44.09-69.32%) |