Table 3 Positive and negative predictive value, sensitivity and specificity of LAMP-CRISPR/Cas for the detection of N. meningitidis in clinical samples
From: An isothermal CRISPR- based lateral flow assay for detection of Neisseria meningitidis
LAMP-CRISPR/Cas | Real-time PCR | PPV | NPV | Sensitivity | Specificity | ||
|---|---|---|---|---|---|---|---|
Positive | Negative | Total | Number/ Total number (%) | ||||
Positive | 50 | 1 | 51 | 50/51 (98.04) | 50/55 (90.91) | ||
Negative | 5 | 83 | 88 | 83/88 (94.31) | 83/84 (98.81) | ||
Total | 55 | 84 | 139 | ||||