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Table 3 Microbiological characteristics of transconjugants

From: Genomic insights into the evolution and mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae co-harboring blaKPC and blaNDM: implications for public health threat mitigation

Isolate

Carbapenemase

MIC (μg/mL)

CRO

CAZ

ATM

TZP

ETP

IMP

SXT

AK

GN

CIP

LEV

FOS

J-JNKPN23

NDM-1

≥ 64

≥ 64

4

≥ 128

≥ 8

≥ 16

≥ 16

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN23-1

NDM-1, KPC-2

≥ 64

≥ 64

16

64

≥ 8

≥ 16

≥ 320

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN24

NDM-1

≥ 64

≥ 64

4

≥ 128

≥ 8

≥ 16

≥ 16

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN26-1

NDM-1, KPC-2

≥ 64

≥ 64

4

≥ 128

≥ 8

≥ 16

≥ 320

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN26-2

NDM-1, KPC-2

≥ 64

≥ 64

4

≥ 128

≥ 8

≥ 16

≥ 320

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN26-3

NDM-1, KPC-2

≥ 64

≥ 64

4

≥ 128

≥ 8

≥ 16

≥ 320

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN26-4

NDM-1, KPC-2

≥ 64

≥ 64

4

≥ 128

≥ 8

≥ 16

≥ 320

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN26-5

NDM-1

≥ 64

≥ 64

4

≥ 128

≥ 8

≥ 16

≥ 16

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN29

NDM-1

≥ 64

≥ 64

2

≥ 128

≥ 8

≥ 16

≥ 16

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN30

NDM-1

≥ 64

≥ 64

4

≥ 128

≥ 8

≥ 16

≥ 16

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN31

NDM-1

≥ 64

≥ 64

≥ 64

≥ 128

≥ 8

≥ 16

≥ 16

≥ 64

≥ 16

≤ 0.25

≤ 0.25

≤ 32

J-JNKPN58

KPC-2

≥ 64

≥ 64

≥ 64

≥ 128

≥ 8

≥ 16

≤ 1

≤ 2

≤ 1

≤ 0.25

≤ 0.25

≤ 32

  1. MIC minimal inhibitory concentrations, CRO ceftriaxone, CAZ ceftazidime, ATM aztreonam, TZP piperacillin–tazobactam, ETP ertapenem, IMP imipenem, SXT trimethoprim–sulfamethoxazole, AMK amikacin, GEN gentamicin, CIP ciprofloxacin, LVX levofloxacin