Fig. 4

Analysis of the virulence and serum resistance of Klebsiella pneumoniae strains. A Survival rates of Galleria mellonella larvae injected with Klebsiella pneumoniae strains. Survival data were plotted using the Kaplan–Meier method, and the groups were compared using the log-rank test. Hypervirulent K. pneumoniae NTUH-K2044 and classic K. pneumoniae ATCC13883 strains were used as lower-virulence comparators. B Evaluation of the serum resistance of ST11 Klebsiella pneumoniae strains. Data are presented as mean (SD). The reference K. pneumoniae strain ATCC 13883 and the hypervirulent strain NTUH-K2044 were used as controls for the susceptible (ATCC 13883) and resistant (NTUH-K2044) grades, respectively. Significant differences (two-tailed unpaired t-test) in viable counts (3 h) of NTUH-K2044 and ATCC 13883 cells are shown in the table. *Unpaired t-test was not used because identical viable counts were recorded. C Virulence gene matrix of Klebsiella pneumoniae strains. The presence and absence of virulence genes are represented by dark blue and light blue boxes, respectively. Red triangles indicate virulence genes located in the plasmids. NTUH-K2044 and ATCC13883 are publicly available K. pneumoniae strains