Table 2 Identification of quorum sensing inhibitors in bioactive metabolites recovered from Halomonas cupida (Halo-Rt1) and Halomonas elongate (Halo-Rt2)
Halophilic bacterial strains | Prospected quorum-sensing inhibitors (QSI) | RT (min.) | Molecular weight | Molecular formula | Mechanism of QSI |
|---|---|---|---|---|---|
Halomonas cupida | Glabrol | 5.92 | 415.2 | C25H28O4 | No previous reports |
5,8-dimethoxyquinoline-2-carbaldehyde | 8.56 | 218.04 | C12H11NO3 | No previous reports | |
Linoleoyl ethanolamide | 13.58 | 324.36 | C20H37NO | No previous reports | |
Agelasine | 19.59 | 458.28 | C26H40N5 | Inhibiting biofilm formation [51]* | |
Penigequinolones derivatives | 20.44 | 468.24 | C16H20N2O6 | No previous reports | |
Berberine | 22.58 | 336.12 | C20H18NO | Disrupting motility, biofilms, pyocyanin, and efflux pumps [53]* | |
Tetracosanoic acid | 23.20 | 391.32 | C24H48O | No previous reports | |
Liquidambaric lactone | 24.88 | 469.32 | C30H44O4 | No previous reports | |
Halomonas elongate | Phloretin | 8.89 | 459.18 | C15H14O | Decreasing swarming and swimming motility [55]* |
Lycoctonine | 17.73 | 468.24 | C25H41NO7 | No previous reports | |
Fucoxanthin | 19.14 | 681.24 | C42H58O6 | Decreasing cell adhesion through the blocking of quorum sensing [56]* | |
Crassicauline | 20.15 | 644.28 | C35H49NO10 | No previous reports |