Fig. 2

Heatmap of the phenotypic and genotypic antimicrobial resistance profile and plasmid replicon numbers of colistin-resistant K. pneumoniae isolates. The phenotypic profile is mapped by white, light blue, and blue colors which respectively correspond to the isolate sensitivity, intermediate susceptibility, and resistance to the antibiotic specified in the column header. The genotypic profile is denoted by dark red or white colors indicating the presence or absence of the corresponding gene, respectively. The green bars on the right illustrate the number of plasmid replicons detected per isolate. The circle symbols on the left indicate the resistance status of the isolates as multidrug-resistant (MDR, pink) or extensively drug-resistant (XDR, grey). PI piperacillin, PIT piperacillin/tazobactam, AMC amoxicillin/clavulanate, CZA ceftazidime/avibactam, CAZ ceftazidime, CTR ceftriaxone, CPM cefepime, AT aztreonam, IPM imipenem, MRP meropenem, ETP ertapenem, AK amikacin, GEN gentamicin, TOB tobramycin, AZ azithromycin, DO doxycycline, TGC tigecycline, CIP ciprofloxacin, LE levofloxacin, SXT sulfamethoxazole/trimethoprim, CT colistin