Fig. 1

Illustration of the multilocus sequence typing (MLST), capsule polysaccharide (CPS), lipopolysaccharide (LPS), wzi and wzc gene alleles, and a heatmap of virulence determinants and heavy metal resistance genes of colistin-resistant K. pneumoniae isolates. On the left, the phylogenetic tree is rooted at the mid-point showing clustering of the isolates by sequence types and visualized by iTOL tool. The virulence pattern is portrayed as gene present (colored) or absent (white) for the following virulence determinants: adherence (light orange), enterobactin (lavender), yersiniabactin (light blue), aerobactin (mid-tone blue), salmochelin (blue), iron uptake system by kfu (dark red), and regulator of mucoid phenotype by rmpA/rmpA2 (light green). Heavy metal resistance genes coding for tellurium (ter), copper (pco), silver (sil), arsenic (ars), and mercury (mer) resistance are denoted as gene present (grey) or absent (white)