Skip to main content

Table 3 Implications of the strength of recommendation for clinicians, patients, and policymakers

From: Pan-American Guidelines for the treatment of SARS-CoV-2/COVID-19: a joint evidence-based guideline of the Brazilian Society of Infectious Diseases (SBI) and the Pan-American Association of Infectious Diseases (API)

Target audience

Strong

Conditional

Policymakers

The recommendation should be adopted as a health care policy in most situations

Substantial debate is required, with the involvement of stakeholders

Clinicians

Most patients should receive the recommended intervention

The health professional should acknowledge that different choices may be appropriate for individual patients and should help them make decisions consistent with their values and preferences

Patients

Most individuals would want the intervention to be recommended, and only a small number would not accept this recommendation

Most individuals would want the intervention to be recommended, although a considerable number would not accept this recommendation

  1. Source: Adapted from Grading of Recommendations Assessment, Development, and Evaluation (GRADE) Working Group. Handbook for grading the quality of evidence and the strength of recommendations using the GRADE approach. Updated October 2013. Available from: [11]