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Table 2 analytical performance of AXDX vs. routine laboratory methods

From: Clinical impact of the accelerate PhenoTest® BC system on patients with gram-negative bacteremia and high risk of antimicrobial resistance: a prospective before-after implementation study

   

Control period

Intervention (AXDX) period

P value

Microbial identification

Time to identification, hrs, median (IQR)

 

30.4 (23.2–36.5)

21.6 (17.6–25)

< 0.0001

 

Failure to identify bi-microbial bacteremia

Assay failurea

NA

5

 
  

Laboratory procedural failureb

NA

1

 

Antimicrobial susceptibility testing

Time to result

 

44.9 (38-48.2)

28.1 (23.9–31)

< 0.0001

 

Minor error

 

NA

18 (3.6%)

 
 

Major error

 

NA

2 (0.4%)

 
 

Very major error

 

NA

2 (0.4%)

 
  1. a Assay failure: AXDX detected only one of two organisms in the sample
  2. b Procedural failure: AXDX correctly detected the organism in the sample, but another blood culture bottle grew a different Gram-negative organism
  3. Abbreviations: AXDX, Accelerate PhenoTest® BC system; IQR, interquartile range