Risk factors of early bacterial infection and analysis of bacterial composition, distribution and drug susceptibility after cadaveric liver transplantation

Table 6 Univariate analysis of risk factors for infections due to bacteria in LT recipients

Variables	Infected recipients (55)	Uninfected recipients (152)	P value
Univariate analysis
Female	16	19	0.005
Age ≥ 50 years	28	49	0.014
Preoperative MELD score ≥ 25	33	71	0.091
Length of hospital stay before LT ≥ 7 days	34	82	0.314
Antibiotic use within 15 days before LT	21	47	0.326
Hepatitis B cirrhosis/liver necrosis/liver cancer	40	116	0.597
Alcoholic cirrhosis	4	10	1
Preoperative type 2 diabetes	9	18	0.394
Infection within 2 months before LT	31	68	0.139
Preoperative WBC ≤ 4 × 10⁹/L	13	54	0.106
Preoperative lymphocyte count < 0.5 × 10⁹/L	9	42	0.097
Preoperative platelet count < 50 × 10⁹/L	16	54	0.387
Preoperative albumin ≤ 30 g/L	17	27	0.041
Cold ischemia time of donor > 360 min	25	70	0.939
Duration of operation ≥ 400 min	27	42	0.004
The intraoperative blood loss ≥ 3000ml	40	76	0.004
The intraoperative RBC transfusion ≥ 12U	37	82	0.087
Basiliximab ≥ 40 mg	32	77	0.338
Antithymocyte globulin	5	9	0.625
Methylprednisolone > 1500 mg	31	90	0.714
ALT on day 1 after LT > 1000U/L	22	41	0.2
Serum creatinine on day 3 after LT > 1.5 mg/dL	9	25	0.989
Postoperative ventilator support	8	8	0.027
Reoperation	3	4	0.577
Acute rejection	4	22	0.167

ISSN: 1476-0711