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Table 4 Factors associated with overall unfavorable outcomes in non-immunodeficient patients with tuberculous meningitis

From: Distinguishing clinical characteristics of central nervous system tuberculosis in immunodeficient and non-immunodeficient individuals: a 12-year retrospective study

Factor

Univariate

Multivariate

Crude OR

(95% CI)

p-value

Adjusted OR

(95% CI)

p-value

Age

1.03(1.01–1.06)

0.003

-

-

HT

4.00(1.49–10.77)

0.006

-

-

Kidney disease

13.00(1.39-121.94)

0.025

-

-

Heart disease

4.22(0.88–20.21)

0.071

-

-

Other comorbidities

3.55(1.18–10.65)

0.024

-

-

Initial GCS score

0.58(0.45–0.74)

< 0.001

0.62(0.49–0.80)

< 0.001

Initial modified BMRC TBM grade III

10.50(1.98–55.72)

0.006

-

-

Cerebral infarction

2.69(1.01–7.15)

0.047

4.18(1.03–14.49)

0.024

Receiving adjunctive corticosteroid therapy

0.34(0.14–0.85)

0.020

0.28(0.08–0.93)

0.037

Temporary ventriculostomy

8.37(1.52–46.03)

0.015

9.67(1.09–85.91)

0.042

  1. Abbreviations: BMRC, British Medical Research Council; GCS, Glasgow Coma Scale; HT, hypertension; OR, odds ratio; TBM, tuberculous meningitis