Determining effects of nitrate, arginine, and ferrous on antibiotic recalcitrance of clinical strains of Pseudomonas aeruginosa in biofilm-inspired alginate encapsulates

Table 1 MIC and MBEC values of antibiotics and ability of the strains to form biofilm

Strain name		Amikacin			Tobramycin			Ciprofloxacin			Biofilm formation
Strain name		S/I/R^b	MIC^c	MBEC^c	S/I/R	MIC	MBEC	S/I/R	MIC	MBEC	(N/W/M/S)^d
Strains isolated from CF^a patients	98–4	S	8	–	S	0.5	–	S	0.5	–	M
	30–1	S	16	–	S	2	–	S	1	–	W
	44–1	S	8	640	S	1	640	S	0.5	160	W
	95–1	S	4	–	S	0.25	–	I	2	–	M
	95–2	I	32	640	S	0.25	–	I	2	–	M
	96–3	S	8	–	S	0.25	–	I	2	–	M
	84–3	S	8	–	S	1	–	R	8	–	S
	94–2	I	32	–	S	1	–	R	8	160	S
	73	I	32	–	R	32	640	R	8	–	W
	98–3	I	32	–	S	1	–	S	0.5	–	S
Reference strains	PAO1	S	2	160	S	0.5	10	S	0.125	20	M

^aCF stands for cystic fibrosis
^bS stands for sensitive, I stands for intermediate-resistant, and R stands for resistant
^cThe values are given as (µg/mL)
^dN stands for non-biofilm producing, W stands for weak biofilm producing, M stands for moderate biofilm producing, S stands for strong biofilm producing

ISSN: 1476-0711