Skip to main content

Table 3 AST profile per bacteria (Enterobacterales)

From: French national epidemiology of bacterial superinfections in ventilator-associated pneumonia in patients infected with COVID-19: the COVAP study

Enterobacterales

Whole-group

Escherichia coli

Klebsiella pneumoniae/sp.

Enterobacter cloacae/sp.

Serratia marcescens

COVID + (n; %)

COVID-(n; %)

p-value

COVID + (n; %)

COVID-(n; %)

p-value

COVID + (n; %)

COVID-(n; %)

p-value

COVID + (n; %)

COVID-(n; %)

p-value

COVID + (n; %)

COVID-(n; %)

p-value

β-lactam (n; % of evaluated in the respective group)

–*

–*

–*

 < 0.05

  

 < 0.05 < 0.05

  

WT

–*

–*

–*

27 (39.1)

6 (42.9)

29 (22.3)/49 (37.7)

9 (90.0)/12 (57.1)

 < 0.05/–a

24 (47.1)/25 (46.3)

4 (40)/6 (50)

–/–

 

Cephalosporinase

–*

–*

–*

6 (8.7)

4 (28.6)

 < 0.05

3 (2.3)/34 (26.2)

0 (0)/4 (19)

–/–

31 (93.9)

8 (88.9)

HC

–*

–*

–*

3 (4.3)

0 (0)

4 (3.1)/25 (19.2)

1 (10.0)/5 (23.8)

–/–

14 (27.4)/14 (25.9)

6 (60)/6 (50)

 < 0.05/–

2 (6.1)

1 (11.1)

e-ESBL

–*

–*

–*

15 (21.7)

1 (7.1)

18 (13.8)/19 (14.6)

0 (0)/0 (0)

–/–a

9 (17.6)/9 (16.7)

0 (0)/0 (0)

–/–

HP

–*

–*

–*

18 (26.1)

3 (21.4)

–/–

CPE

–*

–*

–*

1 (0.8)/3 (2.3)

0 (0)/0 (0)

–/–

4 (7.8)/4 (7.4)

0 (0)/0 (0)

–/–

Aminoglycosides-resistant (n; % of evaluated in the respective group)

72 (13.9)

14 (20.0)

 < 0.05

8 (11.6)

2 (14.3)

20 (0)/23 (17.6)

1 (10.0)/1 (4.8)

–/–

10 (20.8)/10 (19.6)

1 (11.1)/1 (9.0)

–/–

13 (44.8)

1 (12.5)

 < 0.05

Quinolone-resistant (n; % of evaluated in the respective group)

60 (17.8)

7 (9.7)

18 (26.9)

2 (14.2)

18 (32.7)/22 (16.8)

1 (10)/1 (4.8)

–/–

12 (23.5)/12 (22.6)

3 (30)/3 (27.3)

–/–

0 (0)

0 (0)

Fosfomycin-resistant (n; % of evaluated in the respective group)

59 (29.8)

6 (15.0)

a

2 (5.7)

0 (0)

17 (48.6)/40 (47.1)

2 (40)/3 (25)

–/–

6 (22.2)/6 (20)

1 (14.2)/1 (12.5)

–/–

Cotrimoxazole-resistant (n; % of evaluated in the respective group)

67 (18.5)

4 (6.1)

 < 0.05

19 (28.4)

0 (0)

21 (39.6)/23 (18.4)

0 (0)/0 (0)

 < 0.05/–

13 (26.0)/13 (24.5)

2 (20)/2 (18.2)

–/–

0 (0)

0 (0)

  1. WT wild-type, HC hyper-expressed cephalosporinase, e-ESBL Extended-spectrum beta-lactamase producing enterobacterales, Hyper-expressed penicillinase, CPE Carbapenemase-producing enterobacterales, *: non evaluated
  2. aStatistical tendency (p < 0.10)