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Table 4 Detection of drug resistance of three strains exposed to imipenem using the K-B method

From: Evolution of carbapenem resistance in klebsiella pneumoniae and escherichia coli carrying blaNDM−1 gene: imipenem exposure results in sustained resistance memory of strains in vitro

Imipenem (µg/mL)

Inhibition zone (mm)

  

K.pneumoniae TH-P12158

E.coli DH5α-blaNDM−1

E.coli BL21(DE3)-blaNDM−1

0

26.00 ± 2.45

30.00 ± 2.16

26.00 ± 1.63

4

16.33 ± 1.25

17.67 ± 0.47

16.67 ± 0.94

8

13.67 ± 0.47

14.67 ± 0.47

14.33 ± 0.47

12

11.00 ± 0.00

12.67 ± 0.47

13.00 ± 0.82

12 to 8

9.67 ± 0.94

12.33 ± 0.47

13.33 ± 0.47

8 to 4

9.00 ± 1.63

11.00 ± 0.00

11.67 ± 0.94

4 to 0

9.00 ± 0.82

11.00 ± 0.00

12.33 ± 0.47

12 to 0

10.33 ± 0.47

12.67 ± 0.47

13.33 ± 0.94

8 to 0

9.00 ± 1.63

11.33 ± 0.47

12.33 ± 1.25

4 to 0

9.00 ± 0.82

11.00 ± 0.00

12.33 ± 0.47