Table 3 The MIC and MBC values of seven antimicrobial agents against three strains exposed to imipenem
Strains | imipenem(µg/mL) MIC(µg/mL)/MBC(µg/mL) | |||||||
|---|---|---|---|---|---|---|---|---|
IPM | MEM | CXM | CAZ | CSSS | PSTS | LEV | ||
K.pneumoniae TH-P12158 | 0 | 0.5/1 | 0.5/1 | 8/32 | 2/8 | 8/32 | 8/32 | 0.125/0.25 |
4 | 4/8 | 1/4 | 8/32 | 2/8 | 8/32 | 8/32 | 0.125/0.25 | |
8 | 8/16 | 1/4 | 16/64 | 2/8 | 8/32 | 16/64 | 0.125/0.25 | |
12 | 8/16 | 2/8 | 16/64 | 4/16 | 8/32 | 16/64 | 0.125/0.25 | |
12 to 8 | 8/16 | 2/8 | 16/64 | 4/16 | 8/32 | 16/64 | 0.125/0.25 | |
8 to 4 | 8/16 | 2/8 | 16/64 | 4/16 | 8/32 | 16/64 | 0.125/0.25 | |
4 to 0 | 8/16 | 2/8 | 16/64 | 4/16 | 8/32 | 16/64 | 0.125/0.25 | |
12 to 0 | 8/16 | 2/8 | 16/64 | 4/16 | 8/32 | 16/64 | 0.125/0.25 | |
8 to 0 | 8/16 | 2/8 | 16/64 | 4/16 | 8/32 | 16/64 | 0.125/0.25 | |
4 to 0 | 8/16 | 2/8 | 16/64 | 4/16 | 8/32 | 16/64 | 0.125/0.25 | |
E.coli DH5α-blaNDM−1 | 0 | 0.25/1 | 0.25/0.5 | 8/32 | 2/8 | 1/2 | 8/8 | 0.125/0.25 |
4 | 2/4 | 0.5/1 | 16/32 | 2/8 | 4/16 | 16/16 | 0.125/0.25 | |
8 | 4/8 | 0.5/1 | 16/32 | 2/8 | 4/16 | 16/16 | 0.125/0.25 | |
12 | 4/8 | 0.5/1 | 16/32 | 4/16 | 4/16 | 16/16 | 0.125/0.25 | |
12 to 8 | 4/8 | 0.5/1 | 16/32 | 4/16 | 2/8 | 16/16 | 0.125/0.25 | |
8 to 4 | 4/8 | 0.5/1 | 16/32 | 4/16 | 2/8 | 16/16 | 0.125/0.25 | |
4 to 0 | 4/8 | 0.5/1 | 16/32 | 4/16 | 2/8 | 16/16 | 0.125/0.25 | |
12 to 0 | 4/8 | 0.5/1 | 16/32 | 4/16 | 2/8 | 16/16 | 0.125/0.25 | |
8 to 0 | 4/8 | 0.5/1 | 16/32 | 4/16 | 2/8 | 16/16 | 0.125/0.25 | |
4 to 0 | 4/8 | 0.5/1 | 16/32 | 4/16 | 2/8 | 16/16 | 0.125/0.25 | |
E.coliBL21(DE3)-blaNDM−1 | 0 | 0.25/1 | 0.25/0.5 | 8/64 | 4/128 | 2/8 | 2/8 | 0.125/0.25 |
4 | 2/4 | 0.5/1 | 8/64 | 4/128 | 4/16 | 4/16 | 0.125/0.25 | |
8 | 4/8 | 0.5/1 | 8/64 | 4/128 | 4/16 | 4/16 | 0.125/0.25 | |
12 | 4/8 | 0.5/1 | 16/64 | 8/128 | 4/16 | 4/16 | 0.125/0.25 | |
12 to 8 | 4/8 | 0.5/1 | 16/64 | 8/128 | 4/16 | 4/16 | 0.125/0.25 | |
8 to 4 | 4/8 | 0.5/1 | 16/64 | 8/128 | 4/16 | 4/16 | 0.125/0.25 | |
4 to 0 | 4/8 | 0.5/1 | 16/64 | 8/128 | 4/16 | 4/16 | 0.125/0.25 | |
12 to 0 | 4/8 | 0.5/1 | 16/64 | 8/128 | 4/16 | 4/16 | 0.125/0.25 | |
8 to 0 | 4/8 | 0.5/1 | 16/64 | 8/128 | 4/16 | 4/16 | 0.125/0.25 | |
4 to 0 | 4/8 | 0.5/1 | 16/64 | 8/128 | 4/16 | 4/16 | 0.125/0.25 | |