Table 1 Clinical characteristics of 90 patients with cefepime-susceptible Pseudomonas aeruginosa monomicrobial bacteremia receiving cefepime monotherapy
Variables | Valuea |
|---|---|
Demographic parameters | |
Age, year | 66.8 (14.6) |
Male gender | 49 (54.4) |
Concomitant diseases | |
Diabetes mellitus | 29 (32.2) |
Severe renal impairment | 28 (31.1) |
Liver cirrhosis | 10 (11.1) |
Chronic pulmonary disease | 8 (8.9) |
Cerebral vascular accident | 19 (21.1) |
Solid organ malignancy | 39 (43.3) |
Haematological malignancy | 16 (17.8) |
Autoimmune disease | 5 (5.6) |
Clinical conditions | |
Time interval between admission and occurrence of bacteremia, day | 23.2 (36.3) |
Central venous catheter use | 68 (75.6) |
Patients’ severity | |
APACHE II score | 22.07 (6.0) |
Ventilator use | 23 (25.6) |
Intensive care unit stay | 29 (32.2) |
Severe sepsis or septic shock | 21 (23.3) |
Neutropenia | 18 (20.0) |
Source of bacteremia | |
Primary bacteremia | 38 (42.2) |
Lower respiratory tract | 27 (30) |
Urinary tract | 7 (7.8) |
Skin and skin structure | 2 (2.2) |
Central catheter associated blood stream infection | 12 (13.3) |
Intra-abdominal infection | 10 (11.1) |
Treatment | |
Use of maximum cefepime dose | 60 (66.7) |
Treatment duration | 16.4 (7.031) |
Remove catheter or operation | 8 (8.9) |
Outcome | |
30-day crude mortality | 33 (36.7) |