Fig. 6From: A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA)Visualization of the effect of combination of AgNPs, blue light, and azithromycin on MRSA isolate N8 using transmission electron microscope (TEM). The antimicrobial efficacy of the AgNPs at 1/16 MIC, blue light and azithromycin at 0.25 µg/mL alone and in triple combination against isolate N8 was visualized by TEM at ×80,000. The photos show the response of the bacteria to the following treatments: a Drug-free and light-free (control). b AgNPs alone at 1/16 of its MIC. c Blue light exposure at 460 nm and 250 mW for 1 h. d Azithromycin alone at 0.25 µg/mL. e Triple combination of AgNPs, blue light and the azithromycin. Signs of membrane damage and cell lysis were more pronounced in cells treated with a combination of three agents compared to cells treated with each agent alone. Small arrows indicate the location of the AgNPs and the sites of the damageBack to article page