From: Mortality predictors of Staphylococcus aureus bacteremia: a prospective multicenter study
Variable | Fatal (N = 52) | Survivor (N = 203) | Relative risk | [95 % CI] | p value |
---|---|---|---|---|---|
Empirical treatment options | |||||
Peptide antibiotics | 22 (42.3) | 69 (33.9) | 1.32 | [0.81–2.15] | 0.264 |
BL/BLI | 10 (19.2) | 66 (32.5) | 0.56 | [0.29–1.06] | 0.062 |
BL | 9 (17.3) | 31 (15.3) | 1.13 | [0.59–2.12] | 0.719 |
Linezolid | 5 (9.6) | 6 (3.0) | 2.36 | [1.18–4.74] | 0.05 |
Othersa | 6 (11.5) | 31 (15.3) | 1.1 | [0.91–1.24] | 0.495 |
Antibiotic modifications | |||||
De-escalated | 3 (5.9) | 17 (8.4) | 0.67 | [0.26–2.19] | 0.773 |
Escalated | 19 (36.5) | 27 (13.3) | 2.61 | [1.64–4.17] | <0.0001 |
Unchanged | 30 (57.6) | 159 (78.3) | 0.48 | [0.29–0.76] | 0.0024 |