Table 2 Susceptibility of staphylococcal species isolated from cerebrospinal fluid, brain abscess, shunt related and epidural specimen sources. TSN Database USA 2000–2002.
Cerebrospinal fluid | Brain abscess | Shunt related | Epidural abscess | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Organism | Antimicrobial | Total n | %Sa | %R | Total n | %S | %R | Total n | %S | %R | Total n | %S | %R |
Staphylococcus aureus | cefotaxime | 270 | 74.8 | 25.2 | 12 | 75.0 | 25.0 | 10 | 90.0 | 10.0 | NAb | NA | NA |
ceftriaxone | 273 | 71.8 | 27.8 | 13 | 76.9 | 23.1 | 18 | 88.9 | 11.1 | NA | NA | NA | |
levofloxacin | 666 | 73.1 | 22.8 | 48 | 72.9 | 27.1 | 33 | 97.0 | 3.0 | 83 | 79.5 | 18.1 | |
chloramphenicol | 277 | 95.3 | 1.4 | 6 | 100 | 0 | 9 | 88.9 | 0 | NA | NA | NA | |
gentamicin | 941 | 93.0 | 6.8 | 65 | 93.8 | 4.6 | 53 | 94.3 | 5.7 | 38 | 97.4 | 2.6 | |
oxacillin | 1189 | 70.1 | 29.9 | 76 | 67.1 | 32.9 | 71 | 84.5 | 15.5 | 108 | 83.3 | 16.7 | |
rifampin | 851 | 96.9 | 2.5 | 51 | 100 | 0 | 48 | 91.7 | 6.3 | 24 | 100 | 0 | |
TMP-SMXc | 1058 | 95.9 | 4.1 | 72 | 94.4 | 5.6 | 47 | 100 | 0 | 101 | 96.0 | 4.0 | |
vancomycin | 1150 | 100 | 0 | 76 | 100 | 0 | 58 | 100 | 0 | 102 | 100 | 0 | |
Coagulase-negative staphylococci (shunt-related only) | cefotaxime | NDd | ND | ND | ND | ND | ND | 32 | 34.4 | 65.6 | ND | ND | ND |
ceftriaxone | ND | ND | ND | ND | ND | ND | 37 | 35.1 | 64.9 | ND | ND | ND | |
levofloxacin | ND | ND | ND | ND | ND | ND | 75 | 82.7 | 5.3 | ND | ND | ND | |
chloramphenicol | ND | ND | ND | ND | ND | ND | 22 | 95.5 | 0 | ND | ND | ND | |
gentamicin | ND | ND | ND | ND | ND | ND | 124 | 75.8 | 22.6 | ND | ND | ND | |
oxacillin | ND | ND | ND | ND | ND | ND | 183 | 32.8 | 67.2 | ND | ND | ND | |
rifampin | ND | ND | ND | ND | ND | ND | 108 | 92.6 | 6.5 | ND | ND | ND | |
TMP-SMX | ND | ND | ND | ND | ND | ND | 114 | 77.2 | 22.8 | ND | ND | ND | |
vancomycin | ND | ND | ND | ND | ND | ND | 161 | 100 | 0 | ND | ND | ND | |